1.
Indian J Physiol Pharmacol
;
1982 Jul-Sep; 26(3): 215-20
Article
in English
| IMSEAR
| ID: sea-108275
ABSTRACT
Lever pressing rate under a continuous reinforcement schedule for food reward in rats was reduced significantly by cyproheptadine in the dose of 5 and 10 mg/kg body weight. Under fixed ratio schedule of reinforcement, the responding was also suppressed significantly by 5 and 10 mg/kg body weight doses of cyproheptadine. However, high dose (20 mg/kg) of cyproheptadine administered subsequent to the low doses, failed to inhibit the bar pressing rate under either continuous or fixed ratio schedules.